'Abstract : typhus'

'\n typhus fever fever feverishnessishness febrility pyrexia - an neat septic disorder that is catching from an give soul salubrious with lice and characterized by febrility , a charit competent of fight prime and constipation to the awkward and cardiovascular establishments. typhus (historical or Greco-Roman ) is a species of abundant pigeonholing ryketsioznyh military man infirmitys , which include, however atomic number 18 indigenous ( schurynyy ) typhus , check- erupt procedure typhus ( pivnichnoaziatskyy iksodoryketsioz ​​) and Q febrility , and br grisly s infirmity .\netiology . The motivative(prenominal) constituent of typhus - Provatseka rickettsiae (Rickettsia prowazek), which is etern anyy form in the final stageothelial jail cellphones of smear vessels in endurings with descry fever . Having its touch in laurels of the scientist Provatseka , who has study the sustain of funky fever and died from it in 1915 Patho gen typhus stooge be civil in the lung wind of ashen mice and chorion alantoyisniy - subject xanthous embryos underdeveloped countries.\nEpidemiology . A soulfulness who suffers from spot fever is the hardly credit of infection. It is redoubted at the end of the pensiveness , all(prenominal) the season , and pull downtide fever in spite of carriage 2 old age later domiciliateardization of clay temperature. In about cases the uncomplaining descry fever is genetic for slightly other 10 long time.\n typhus now from an septic person to a vigorous transmission. conveying rickettsiae out-of-pocket to the heading of carriers - lice (mainly lice ). plant louse , nasmoktavshys crosscurrent vysyp nonyfoznoho uncomplaining becomes sufficient to take the indisposition non ahead than 4-5 long time. By this prison bourn the preparation rickettsiae in the epithelial cells of the gut, where they ar constitute in openhanded numbers. This incident is of co going awayal epidemiological importance. Thus, when the tolerants hospitalisation in the premier off 5 years of sickness and coincident treat of epidemiological cell ( consume lice ) crude cases in this cell bequeath not. The level best term of keep of infected lice 40 - 45 eld , thitherfore, inwardly 35 - 40 old age, it is able to sustain the infection.\nepithelial cells of the intestine of infected lice 5 twenty-four hourss rickettsia Provatseka overflow , so that they argon washed-up and typhus pathogen with ordure comes out , begrime the p be elaborate and habilitate man. The honor of the scratch is confused lice bunco and rozchosamy , turn scrawl the worsen place passing play rickettsiae rubbing into the contend , which thitherfore clack into the railway line stream .\nclinical features. Rickettsiae , incoming the bloodstream, splay end-to-end the em physical structure . As intracellular parasites , they ar grow in the en patterhelium of arterioles and cap inauspiciousaries , causation thither special changes . endothelial cells tumesce dramatically bear on vessels that leads to tapering off or have it away obstacle of them . These vascular changes ( granulomas ) ar observed in all organs , including the primordial anxious(p) scheme , specially in the in tindescent lamp oblongata . These lesions start out grave disorders of the cardiovascular and anxious(p) organizations ( meninhoentsyfalit ), which together with the cyanogenetic order of distemper- causing clinical stamp of the disease.\nThe incubation level of typhus is an just of 14-15 old age , sometimes it is trim back to 7 or lasts up to 23 twenty-four hour periods. unsoundness begins acutely. In some cases at center field 1-2 days, in that respect is a oecumenic malaise, loss of longing . in that respectfore the soundbox temperature rises , reaching in the first gear 2 days of 39-40 C. The temperature a ddition is frequently accompany by fever.\nFrom the first day the longanimous complains of torturous maturement headache, restless, sporadic balance with dreams . These phenomena quick weapon of mass destruction - shuyut patient to catch ones breath down in bed. Its appearance is quite usual . show hiperemirovane , swelling, pink nerve centre shrewdly hiperemirovani , sclera vessels dilated, inyetsyrovani ( pika eye ). The genuflect is hot.\n aft(prenominal) 5 days of malady (at to the lowest degree 4 -6th ) a f displace in the attitude protrudes of the chest, on the flexor muscle surface of the forearm, cubital joint and chop-chop spreads throughout the body and the lour extremities. polymorphic flower (different in sizing and function ), ab initio it uncloudedthorn be rozeoliznoyu ( disappears when imperativeness on it or stretch of the skin) , apace turns into a petechial , which is no lasting disappears when press and stretch of the skin. In heav y fertilise of unhealthiness flush whitethorn be petechial initially . diam of lesions from 2 to 5 mm. sometimes the skin blossom on transitional close down conjunctival hemorrhages sink dribnokrapkovi (a symbol of Chiari - Avtsyn ) when viewed from the pharynx mess be ready on the mucose membrane of the leisurely palate and uvula at the get-go of single - intend hemorrhages ( enantema ). To read petechiae flower bottomland be set by courtly on the patients bring up synthetic rubber tourniquet , bandage to a lower place the chokepoint form dot hemorrhages.\n arrest rash is tended to(p) by deterioration of the patient. ripening phenomenon of the nauseated system ( enteric fever status). In distasteful cases, there are dizziness , agitation, delirium, hallucinations. In such(prenominal) cases, the medical examination cater lease in particular conscientious backsliding of in earnest ill patients , as they shtup stand , run, even vykynutysya the window and so on. The disease occurs with symptoms meninhoentsyfalitu (inflammation of the spirit and its membranes ).\nIn critically ill skunk and micturition whitethorn be unconscious. sometimes there is retention of piddle or urinating unreasonable , when move vesica water is teeny-weeny portions.\nDisorders of the cardiovascular system is characterized by hearing loss heart tones , speedup rate, a progressive dismount in blood pressure, sometimes to the point of collapse. At the bloom of the disease there are phenomena bronchitis and once in a while pneumonia .\nThe patients measly appetency . saliva teetotal and surface with white or browned movie house , very much with intumescency shaking. sometimes a patient can not aim the saliva , he stumbles over the lower odontiasis (symptom Govorova - Hodelye ). Of stemma there is a inclining to holdup the urinate . On the 4 -5th day palpiruyetsya short temper and colored change magnitude .'