The Effects of Lsd Essay Example for Free

The Effects of Lsd Essay LSD was first synthesized on November 16, 1938 by Swiss chemist Albert Hofmann at the Sandoz Laboratories in Basel, Switzerland as part of a large research program searching for medically useful ergot alkaloid derivatives. LSDs psychedelic properties were discovered 5 years later when Hofmann himself accidentally ingested an unknown quantity of the chemical. The first intentional ingestion of LSD occurred on April 19, 1943, when Hofmann ingested 250 mg of LSD. He said this would be a threshold dose based on the dosages of other ergot alkaloids. Hofmann found the effects to be much stronger than he anticipated. Sandoz Laboratories introduced LSD as a psychiatric drug in 1947. Beginning in the 1950s the US Central Intelligence Agency began a research program code named Project MKULTRA. Experiments included administering LSD to CIA employees, military personnel, doctors, other government agents, prostitutes, mentally ill patients, and members of the general public in order to study their reactions, usually without the subjects knowledge. The project was revealed in the US congressional Rockefeller Commission report in 1975. In 1963 the Sandoz patents expired on LSD. Also in 1963, the US Food and Drug Administration classified LSD as an Investigational New Drug, which meant new restrictions on medical and scientific use. [ Several figures, including Aldous Huxley, Timothy Leary, and Al Hubbard, began to advocate the consumption of LSD. LSD became central to the counterculture of the 1960s. On October 24, 1968, possession of LSD was made illegal in the United States. The last FDA approved study of LSD in patients ended in 1980, while a study in healthy volunteers was made in the late 1980s. Legally approved and regulated psychiatric use of LSD continued in Switzerland until 1993. Today, medical research is resuming around the world. Lysergic acid diethylamide, abbreviated LSD or LSD-25, also known as lysergide (INN) and colloquially as acid, is a semisynthetic psychedelic drug of the ergoline family, well known for its psychological effects which can include altered thinking processes, closed and open eye visuals, synesthesia, an altered sense of time and spiritual experiences, as well as for its key role in 1960s counterculture. It is used mainly as an entheogen, recreational drug, and as an agent in psychedelic therapy. LSD is non-addictive, is not known to cause brain damage, and has extremely low toxicity relative to dose. However, adverse psychiatric reactions such as anxiety, paranoia, and delusions are possible. LSD was first synthesized by Albert Hofmann in 1938 from ergotamine, a chemical derived by Arthur Stoll from ergot, a grain fungus that typically grows on rye. The short form LSD comes from its early code name LSD-25, which is an abbreviation for the German Lysergsaure-diethylamid followed by a sequential number. LSD is sensitive to oxygen, ultraviolet light, and chlorine, especially in solution, though its potency may last for years if it is stored away from light and moisture at low temperature. In pure form it is a colorless, odorless, tasteless solid. LSD is typically delivered orally, usually on a substrate such as absorbent blotter paper, a sugar cube, or gelatin. In its liquid form, it can also be administered by intramuscular or intravenous injection. LSD is very potent, with 20–30 Â µg (micrograms) being the threshold dose. New experiments with LSD have started in 2009 for the first time in 40 years. Introduced by Sandoz Laboratories, with trade-name Delysid, as a drug with various psychiatric uses in 1947, LSD quickly became a therapeutic agent that appeared to show great promise. In the 1950s, officials at the U. S. Central Intelligence Agency (CIA) thought the drug might be applicable to mind control and chemical warfare; the agencys MKULTRA research program propagated the drug among young servicemen and students. The subsequent recreational use of the drug by youth culture in the Western world during the 1960s led to a political firestorm that resulted in its prohibition. Currently, a number of organizations—including the Beckley Foundation, MAPS, Heffter Research Institute and the Albert Hofmann Foundation—exist to fund, encourage and coordinate research into the medicinal and spiritual uses of LSD and related psychedelics. LSD can cause pupil dilation, reduced or increased appetite, and wakefulness. Other physical reactions to LSD are highly variable and nonspecific, some of which may be secondary to the psychological effects of LSD. Among the reported symptoms are numbness, weakness, nausea, hypothermia or hyperthermia, elevated blood sugar, goose bumps, heart rate increase, jaw clenching, perspiration, saliva production, mucus production, sleeplessness, hyperreflexia, and tremors. Some users, including Albert Hofmann, report a strong metallic taste for the duration of the effects. LSD is not considered addictive by the medical community. Rapid tolerance build-up prevents regular use,[citation needed] and cross-tolerance has been demonstrated between LSD, mescaline[ and psilocybin. This tolerance diminishes after a few days after cessation of use and is probably caused by down regulation of 5-HT2A receptors in the brain. LSDs psychological effects (colloquially called a trip) vary greatly from person to person, depending on factors such as previous experiences, state of mind and environment, as well as dose strength. They also vary from one trip to another, and even as time pass during a single trip. An LSD trip can have long-term psych emotional effects; some users cite the LSD experience as causing significant changes in their personality and life perspective [citation needed]. Widely different effects emerge based on what Timothy Leary called set and setting; the set being the general mindset of the user, and the setting being the physical and social environment in which the drugs effects are experienced. Some psychological effects may include an experience of radiant colors, objects and surfaces appearing to ripple or breathe, colored patterns behind the closed eyelids (eidetic imagery), an altered sense of time (time seems to be stretching, repeating itself, changing speed or stopping), crawling geometric patterns overlaying walls and other objects, morphing objects, a sense that ones thoughts are spiraling into themselves, loss of a sense of identity or the ego (known as ego death), and other powerful psycho-physical reactions. Many users experience dissolution between themselves and the outside world. This unitive quality may play a role in the spiritual and religious aspects of LSD. The drug sometimes leads to disintegration or restructuring of the users historical personality and creates a mental state that some users report allows them to have more choice regarding the nature of their own personality. If the user is in a hostile or otherwise unsettling environment, or is not mentally prepared for the powerful distortions in perception and thought that the drug causes, effects are more likely to be unpleasant than if he or she is in a comfortable environment and has a relaxed, balanced and open mindset. LSD causes an altered sensory experience of senses, emotions, memories, time, and awareness for 6 to 14 hours, depending on dosage and tolerance. Generally beginning within thirty to ninety minutes after ingestion, the user may experience anything from subtle changes in perception to overwhelming cognitive shifts. Changes in auditory and visual perception are typical. Visual effects include the illusion of movement of static surfaces (walls breathing), after mage-like trails of moving objects (tracers), the appearance of moving colored geometric patterns (especially with closed eyes), an intensification of colors and brightness (sparkling), new textures on objects, blurred vision, and shape suggestibility. Users commonly report that the inanimate world appears to animate in an unexplainable way; for instance, objects that are static in three dimensions can seem to be moving relative to one or more additional spatial dimensions. Many of the basic visual effects resemble the phosphine seen after applying pressure to the eye and have also been studied under the name form constants. The auditory effects of LSD may include echo-like distortions of sounds, changes in ability to discern concurrent auditory stimuli, and a general intensification of the experience of music. Higher doses often cause intense and fundamental distortions of sensory perception such as synesthesia, the experience of additional spatial or temporal dimensions, and temporary dissociation. The potential uses of LSD end of life anxiety, alcoholism, pain, cluster headaches, spiritual, and creativity. These are the potential adverse effects: adverse drug interactions, mental disorders, and suggestibility and also psychosis.

Segregation and Civil Rights Essay -- Black Civil Rights in America

The definition of the term â€Å"American character†, in general, was in fact plagued during the 1950s. Instead of the believable â€Å"picture perfect† definition that American character was portrayed to be, it was really constructed of major struggles between different races. In particular, the significant struggles between blacks and whites. The 1950s was a crucial decade of change for African Americans. The results of the battle for nine African American children to attend Central High School (Little Rock, Arkansas) in 1957 promoted social advance for the permanent desegregation of public school systems. However, even with this nationally recognized social advance, the concept of â€Å"American character† varied between blacks and whites due to racial and social inequality. Back in 1896, the United States Supreme Court ruled in Plessy v. Ferguson that racial discrimination was constitutional. This decision gave the states permission to segregate citizens by race and to operate â€Å"separate but equal† facilities all around. Terrence Roberts, in his novel Lessons from Little Rock, shares his first-hand experience of neglect from society. Roberts states, â€Å"As a black person, I had no legal right to assume that I could participate fully in civic, educational, economic, political, or social affairs† (Roberts 19). Whites lived in great satisfactory after this decision. They remained the group with the upmost authority and continued to mistreat blacks at any cost, including denying them the right to an equal quality of education. Their definition of American character, being the wealthiest and the smartest, was still acknowledged as the existence of African Americans became more and more surreal. In 1954, the Supreme Court ruled in Brown v. Boa... ... Kirp, David L. Political Science and Politics, Retreat into Legalism: The Little Rock School Desegregation Case in Historic Perspective Vol. 30, No. 3 (Sep., 1997), pp. 443-447 Published by: American Political Science Association. (http://www.jstor.org/stable/420120) Lawson, Steven F. and Payne, Charles. ""Mob Rule Cannot Be Allowed to Override the Decisions of Our Courts": President Dwight D. Eisenhower’s 1957 Address on Little Rock, Arkansas." History Matters: The U.S. Survey Course on the Web. Lanham, Maryland: Rowan & Littlefield Publishers, Inc., 1998. Web. . Reumann, Miriam G. American Sexual Character: Sex, Gender, and National Identity in the Kinsey Reports. Berkeley and Los Angeles: University of California Press, 2005. Roberts, Terrence J. Lessons from Little Rock. Little Rock, AR: Butler Center, 2009. Print

Downtown Health Care Clinic Essay

Perpetual Mercy Hospital Perpetual Mercy is a successful, nonprofit hospital located in the southern periphery of a major western city. It is extremely financially stable, debt free and holds the highest occupancy rate in amongst all hospitals located in its metro location. Perpetual Mercy has become extremely dependent on older, inner city occupants that are covered by Medicaid. More business is becoming minor, short stayed visits which have begun to jeopardize the financial stability of the hospital. Other major threats that Perpetual Mercy faces are the demographic shifts in the community, in which northern suburban areas are becoming more heavily occupied, placing potential business farther away from the hospital. Downtown Healthcare Clinic In 1998 Perpetual Mercy Hospital’s Board of Trustee’s did a study to find out if it would be worthwhile to open a clinic up north in a new construction area downtown. The clinic would offer specific services like: Preventive health care Minor emergency care Referral for acute and chronic health care conditions Specialized employer services Primary health care services Basic x-ray and lab test The clinic would not only service the local community but also serve as a preferred provider organization (PPO), holding a contractual arrangement with employment groups located near the new clinics area. These services will allow the hospital to expand their referral base, increase referrals of privately insured patients and establish a liaison with the business community by addressing employees’ specific health care needs. A study of the service radius showed that the clinics services would cover a 5 block radius and approximately 11,663 office workers, with a projected population growth of 6% per year because of new area construction. After interviewing 400 office workers in the area, results showed that 50% of office workers in  the area would use the clinic if necessary and 40% would visit the clinic at least once in the first year. Due to the study results Perpetual Mercy Hospital’s Board of Trustee’s decided that it would be beneficial to open the clinic in 1999. The clinic would be open 260 days a year, Monday through Friday from 8:00am to 5:00pm. The hospital projected to be self-supporting after the 3rd year of business. DHC’s First Year of Operations After the first year of operations DHC had met their expectations. They had made 105 referrals to Perpetual Mercy, produced $378,000 in revenue and had a net profit of $30,000. The top reasons for patient visits were: Personal illness exams 53% Workers compensation exam/treatment 25% Employment/ insurance physical exams 19% Emergency 3% 97% of visits in the year one were first time users with 113 visits by repeat patients. Most visits took place between October 1999 and March 2000. The average revenue per patient was $67.90 with expected increase of 8% per visitor beginning May 2000. Visits consisted of 60% women and 40% men.

Age Appropriate Toys

Play is vital for learning in children. It is equally important that the toys and the materials that are used to make them are age appropriate for the children using them. Your child’s current developmental stage plays a major role in toy selection (Frost, Livestrong.com) As a general rule, you should always make sure that toys for young children are safe. Toys should be well made; not easily shattered, or broken.Small children, even up to preschool age, still tend to put objects in their mouths if the pieces are small enough. Poor construction increases this risk of small parts coming off while your child plays with the toy (Frost, Livestrong.com). If painted, the toy should always be painted with non- toxic lead free paint. It is also important that a toy can be easily cleaned and disinfected to prevent the spread of germs (Good Toys for Young Children, NAEYC).Very young babies enjoy looking at people and objects, therefore, toys with faces or bright colors would be excellen t for that age (Good Toys for Young Children, NAEYC). As children grow and begin practicing their fine motor skills, toys that require small movements would be a great fit. Stacking blocks or cups would be very helpful (Frost, Livestrong.com).The characteristics of toys, their safety, and how they may be used or abused is very important when selecting toys for your child. Understanding your child and their abilities and needs will help in choosing appropriate toys. Visualizing how each individual child would play with a toy will help you to determine the educational value it offers (Frost, Livestrong.com).Part 2Developmentally Appropriate Toy for Ages 6-12 MonthsFisher-Price Rainbow Snail StackerThis cheery snail’s base wobbles and make sounds when batted at. The colorful arches of his back are removable and stackable for exciting play! This toy allows a child to practice and progress their fine motor skills. As the baby learns to distinguish different colors he/she will begi n to develop thinking skills. The snail’s bright and exciting colors as well as the entertaining sounds it creates will attract the child. Parents will enjoy this toy as well as children because it is made of safe materials, does not take up a lot of room, is easily cleaned, helps the child to learn, and most importantly brings happiness to their children. This is a very positive, age appropriate toy for this stage of development.Laugh and Learn to Play PuppyThe Laugh & Learn Learning Puppy will definitely entertain your child. The toy merges learning with two different musical modes – learning mode and game mode. In learning mode, the puppy teaches the alphabet, different body parts, and colors through song. When you switch to the game mode, the puppy encourages interactive play, giving fun word play for the baby. This is an awesome toy for this age group. The soft material, light up heart, and sing along songs stimulate the child’s senses.When in game mode, th e child will work on hand and eye coordination, as the puppy responds to the baby’s touch. The bright colors and fun songs of this precious pup attract and keep the babies attention. A parent would be very satisfied with toy because it teaches the baby letters, numbers, feelings, and parts of the body. It is also soft and plush, so even when turned off can be a comfort to the child. I would definitely choose this toy. It touches many of the different learning needs of children in this age group.Growing Baby Elephant Shape SorterThe Growing Baby Elephant Shape Sorter is tons of fun! The friendly elephant head moves from side to side. This toy features 8 shape blocks: 2 circles, 2 triangles, 2 squares and 2 stars for a fun filled game of fill and spill. This would be an excellent choice for this developmental stage. The brightly colored blocks will help the baby start to identify different shapes and  colors.Putting blocks in and taking them out of the base will refine the ch ild’s eye and hand coordination. The repetitiveness would be very appealing to a young child as well as the colorful blocks and happy looking elephant. Any parent would select this toy as it is educational, safe, and made from an easily cleaned material. I would definitely select this toy for my child. It helps to refine their fine motor skills as well as helping the child with problem solving skills as they work to fit the correct shapes in the holes. This is a great fit for any child six to twelve months old.

Essay Sample on the Persian Gulf War

Essay Sample on the Persian Gulf War Free sample essay on The Persian Gulf War: The Persian Gulf War, also known to Americans a Operation Desert storm, was one of the most defining events in American history. It was the one war that Americans fought in and had very little loss of life! Said mother when I asked her about the war and what she thought of it. And that was very true since almost all of the 500,000 troops sent into Kuwait came home safe and sound. This war was also one of technological superiority which greatly favored American forces. The use of guided bombs, missiles and almost invisible planes made it easy for the American forces to take out key targets on the Iraqi battle ground. The war began because the Iraqi dictator Saddam Hussain believed that Kuwait was over producing oil and that they stole oil form other oil fields. This quickly escalated to an all out war and had the oil-thirsty man Saddam and his troops stormed into Kuwait with guns in hand and thoughts of destruction and greed on their minds. This upset American president George Bush who immediately gave a call to congress to act against this devilish crook who struck fear into the eyes of his enemies and his own suffering people. Congress agreed and Bush sent in 500,000 men to fight for the liberation of Kuwait and its valued natural recourse. Stealth bombers, F-15 fighter jets, and B-2 bombers bombarded the Kuwaiti soil demolishing any and all Iraqi military targets and clearing a path for the American clean up crew, who with great ease took out any remaining resistance. The Persian Gulf War though short gave new self pride and honor to American people said my father after reflecting on the wars outcome. And that is so true, because today American people stand proud next to their leader knowing that he will serve his country and his countries people to the fullest of his abilities. Giving us a safe home and a powerful, capable army to support us and rush blindly into battle to protect the country they so love and care for. This is what makes this country the greatest country on earth and is still being proven today on the battle grounds of Iraq. Where men and women fight side by side for the greater good and to defend the innocent of the world.

Best College Planners 9 Apps for Managing Your Studying and Finance

Best College Planners 9 Apps for Managing Your Studying and Finance The technological era that we live in makes our lives easier every day. Now you dont need to go and buy a daily planner to fill out with your pencil – you can just download the app and have all of your weekly and monthly plans right at hand. But there are so many apps available on the market, so how can you choose the one that will be convenient particularly for you? We explored the majority of the existing apps to make a list which you can use to pick the app that will be handy for you. So, lets dive into the digital world and discuss features of the most used apps are. Education 1 myHomework Student Planner Price: Free or $4.99 Premium per year Rating: 4.6 The planner is very simple to use, and it has an attractive interface. You just need to add your classes to the general schedule or specify the days of the week and the time for your extracurricular activities. The best feature of this app is the ability to add the due dates and quick notes about each assignment that you have to complete while tracking the deadlines – you will see which due dates are upcoming. You can download the app from the AppStore  or GooglePlay. 2 My Study Life Price: Free Rating: 4.7 This app is one of the most popular college student planners, and it is all about having all of your classes and exams schedules placed in your pocket. If you struggle with remembering the dates of your tests or assignment due, choose this app. It is especially convenient for students who have two-week timetables. This is one of the best organizers for college students which you can get for free. This application allows you to sync your notes and plans across all of your devices, track assignment progress and get customized reminding notifications about upcoming classes or exams. The app is available for various kind of devices on iOS, Android, and Windows. Feeling stressed for upcoming finals? Check out the article which will help you to survive through the finals week. 3 Egenda Price: Free Rating: 4.7 Egenda is a popular app among high school and college students due to its convenience and utility. This is a perfect option to choose when you need a helper for: Scheduling your day Reminding about the assignments that are due Adding notes and timetables Egenda is used by so many students because it is simple to use and completely free. You can manage your tests, exams and even quizzes. Notes can be sorted by classes or even the due date which helps you to be right on time with your homework. If you have to perform a task for your English class, check out another list of the useful apps that we have gathered for you the list of apps to make you fluent in English. This app is definitely more useful than a regular daily planner or a 12 months planner, and its always with you to remind you about the next class or test. Available for download from AppStore and GooglePlay. 4 School Planner Price: Free Rating: 4.6 If you havent heard about this app yet, then you probably live under the rock because the majority of students say that School Planner is one of the most powerful personalized planners for college students with an attractive interface. The beauty is in the simplicity of the interface and handy features, such as the abilities to: record lectures manage tasks, grades and subjects create customized timetables It syncs within all your devices, providing a backup in case of need, saves teachers contact info, and calculates average grade automatically. Get it for your Android right now! 5 HomeworkApp Price: Free Rating: 4.7 The name of this app speaks for itself. This is what your parents wish theyd had when they were in college and what now you can have on your phone. It is a simple yet very effective and helpful tool to organize all the homework assignments. Goal setting, progress tracking, customizable calendar and many more other features of this app are the main reasons for many students all over the world to use it on a daily basis. This app is a perfect way to get convenient weekly spreads and customizable design at the same time. Download it for your Android. 6 Timetable Price: Free Rating: 4.2 If you are looking for something more minimalistic, then this app is for you. You can create a schedule for the whole year. The only thing you need to do is to add the information about your classes and exams. You can adjust your schedule according to the cycle of one, two, three or four weeks, get notifications and search in your classes or tasks. Get the app on Google Play and enjoy your perfect layouts which, as the users of digital monthly planners say, are very convenient for both college and high school students. Financial Planning for Students Many college students face the need to track not only their studies but also their budget. Its often hard to stick to your limited budget when there are so many events that you want to attend. If you want to use your money rationally and find a useful tool for college financial planning, download one of these useful finance planning apps. 7 Mint Price: Free Rating: 4.7 If you need to track your spendings throughout your school year, choose this app and plan your budget without any struggles. Mint allows you to keep information about your bank accounts and bills together, sort your spendings by the categories, and track credit usage. Get it on Google Play or App Store. 8 Money Manager Expense and Budget Price: Free Rating: 4.6 Would you like to have a personal accountant to manage your budget? If hiring one is too expensive for you, then just download this app and have all of your expenses completely organized and tracked. If you wonder how much money you can spend on a party and with no damage to your monthly budget, you can calculate it with this simple but effective manager. Also, you can manage your cards and get instant monthly statistics of your incomings and expenses. Available for iOS and Android. 9 Goodbudget: Budget Finance Price: Free Rating: 4.6 No more struggling with a budget for college students. Download the app and start tracking all of your spendings. Learn how to plan your budget and manage your credit cards and cash. Any college student who frequently runs out of money needs such a helper. Especially, if you need to stick to the limited budget that you can spend on groceries (by the way, we also have great ideas on how you can eat well and save your money). Available for Android and iOS. Wrapping Up We hope you liked our list of the best college planners and organizers and found it useful. Having such a helper available all the time can make your studying much easier and also teach you some time and budget management skills.

Longitudinal Strategy Essay Example | Topics and Well Written Essays - 2250 words

Longitudinal Strategy - Essay Example These include vaccines, over-the-counter medicines as well as other broad range of health-consumer related products. The company therefore has a profile of operating in the different segments of pharmaceutical and consumer healthcare products within the UK as well as other parts of the world. Besides operating on medical supplies and research, GSK produces other health products such as beverages, which are used worldwide. Besides the operations of the company within the UK market, the company has major markets within the US, Germany, Italy, Japan, Spain as well as in France (StockMarketsReview.com, 2013, para 1). GSK, as a trading company, has a statement of mission, which is provision and development of immunotherapeutic, as well as vaccines that are necessary for improvement of human health globally. The company has made strategic milestones in the field over years and is credited for having great and significant contributions towards the global health as it is today. The company’s profile reveals that the formation of the company as it is today has involved merger efforts by many companies and thus would have a history from the early years of 20th century. It has also made great development milestones in the past since the millennium, where the scope of this paper will be. This paper intends to evaluate the strategic development milestones that the company has undergone with a special attention to the last thirteen years (since 2000). This is because the existence of the corporate identity of GlaxoSmithKline plc is only that old from the merger of SmithKline Beecham and Glaxo Wellco me in December 1999 (Addison and Lawson 2012: 3-5). In line with the company’s strategic mission, it has special focus on some fundamental areas such as realizing sustainable growth, improving long-term financial performance as well as reducing risks. The company realizes these goals through embracing diversification in global business, delivering high-value products as well as adoption of simplified business models. The recent developments have seen the company adopt generic branded manufacturing to add to the previously existing patented strategies in order to command higher influence and relevance in the modern day market. Addison and Lawson through a recent discourse analysis study concerning the strategic development move of generic branding found out that this was necessary and very effective in lowering the associated performance risks as well as in increasing the range of products being traded on. Research studies show that the shift in production models into the inco rporation of generic manufacturing has greatly revolutionized the industry through lowering the costs of production and in the process lowering the prices of the commodities on offer. Through the move, the GSK is able to manufacture cheap pharmaceutical products through lowered costs in research as well as in awareness creation. The move was strategic in that it enabled the company to focus the competitive strategies in manufacture of the trading products at higher efficiencies in order to continue in the lead over the world market amidst heightened competition (Addison and Lawson 2012: 32). In fact, it is through such a move that the company is acknowledged to diversify